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Wednesday, November 30, 2011
Tuesday, November 29, 2011
BWH researchers develop a vaccine prototype stronger than traditional vaccines
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Public release date: 28-Nov-2011[ | E-mail |
Share ] Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital
BOSTON, MABrigham and Women's Hospital (BWH) researchers have created a vaccine that is more potent than traditional vaccines available today. The glycoconjugate vaccine prototype is 100 times more effective than traditional glycoconjugate vaccines. Their work is published in the December 2011 issue of Nature Medicine.
A glycoconjugate vaccine is comprised of covalently bound carbohydrate and protein molecules, and is the standard design for many vaccines used to protect against common diseases such as pneumonia and meningitis.
Researchers designed the vaccine prototype after discovering that immune cells, called T-cells, can recognize a vaccine's carbohydrates, and from that recognition elicit an immune response. This discovery challenges popular assumptions that immune cells only recognize the protein portion of glycoconjugate vaccines.
Proof that T-cells recognize carbohydrates came when researchers immunized mice with different types of glycoconjugate vaccines against the bacteria, group B Streptococcus. One group was immunized with vaccines containing different proteins. Another group was immunized with vaccines with the same proteins. For both groups, the carbohydrate chain in the vaccines was the same.
Researchers saw that mice given the vaccines with different proteins had just as good an immune response as those given vaccines with the same proteinsthe variability in proteins did not change immune response. This told researchers that T-cells were recognizing carbohydrates to generate a consistent immune response. They further investigated the mechanisms responsible for how carbohydrate-containing glycoconjugate vaccines activate protective immunity to a bacterial infection.
"One thing that is tremendously novel here is that we were able to find T-cells within a mouse after immunization with a glycoconjugate [vaccine] that just recognized carbohydrates," said Dennis L. Kasper, MD, director of BWH's Channing Laboratory. "So these may be the first true carbohydrate-specific T-cells found."
The understanding that it was not only proteins, but also carbohydrates that were being recognized by cells led researchers to design a vaccine that yielded many carbohydrate particles when processed by the immune systemin turn creating a vaccine that generated a stronger immune response. Researchers believe that the more effective vaccine prototype they designed may one day assist in protecting high-risk populations susceptible of disease.
"For example, pneumococcal conjugate vaccines are good in children, but are not effective in protecting the elderly," explained Kasper. So we are hopeful that by designing vaccines like this, you'll make better vaccines that will be effective in all the at-risk populations."
Fikri Avci, PhD, lead study author and instructor in the Department of Medicine at BWH and Harvard Medical School adds that the findings on how the body's immune cells interact with carbohydrates will also lead to more effective vaccines in the future.
"Carbohydrates are among the most abundant and structurally diverse molecules in nature," said Avci. "They are extremely important in many biological functions. A better understanding of carbohydrate interaction is crucial. We are hoping that our findings will provide a framework for production of new-generation therapeutics and preventive medicines not only against bacterial infections, but also for cancer and viral diseases."
###
The research was supported by grants from the United States National Institutes of Health.
Brigham and Women's Hospital (BWH) is a 793-bed nonprofit teaching affiliate of Harvard Medical School and a founding member of Partners HealthCare, an integrated health care delivery network. BWH is the home of the Carl J. and Ruth Shapiro Cardiovascular Center, the most advanced center of its kind. BWH is committed to excellence in patient care with expertise in virtually every specialty of medicine and surgery. The BWH medical preeminence dates back to 1832, and today that rich history in clinical care is coupled with its national leadership in quality improvement and patient safety initiatives and its dedication to educating and training the next generation of health care professionals. Through investigation and discovery conducted at its Biomedical Research Institute (BRI), www.brighamandwomens.org/research, BWH is an international leader in basic, clinical and translational research on human diseases, involving more than 900 physician-investigators and renowned biomedical scientists and faculty supported by more than $537 M in funding. BWH is also home to major landmark epidemiologic population studies, including the Nurses' and Physicians' Health Studies and the Women's Health Initiative. For more information about BWH, please visit www.brighamandwomens.org.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Public release date: 28-Nov-2011[ | E-mail |
Share ] Contact: Marjorie Montemayor-Quellenberg
mmontemayor-quellenberg@partners.org
617-534-2208
Brigham and Women's Hospital
BOSTON, MABrigham and Women's Hospital (BWH) researchers have created a vaccine that is more potent than traditional vaccines available today. The glycoconjugate vaccine prototype is 100 times more effective than traditional glycoconjugate vaccines. Their work is published in the December 2011 issue of Nature Medicine.
A glycoconjugate vaccine is comprised of covalently bound carbohydrate and protein molecules, and is the standard design for many vaccines used to protect against common diseases such as pneumonia and meningitis.
Researchers designed the vaccine prototype after discovering that immune cells, called T-cells, can recognize a vaccine's carbohydrates, and from that recognition elicit an immune response. This discovery challenges popular assumptions that immune cells only recognize the protein portion of glycoconjugate vaccines.
Proof that T-cells recognize carbohydrates came when researchers immunized mice with different types of glycoconjugate vaccines against the bacteria, group B Streptococcus. One group was immunized with vaccines containing different proteins. Another group was immunized with vaccines with the same proteins. For both groups, the carbohydrate chain in the vaccines was the same.
Researchers saw that mice given the vaccines with different proteins had just as good an immune response as those given vaccines with the same proteinsthe variability in proteins did not change immune response. This told researchers that T-cells were recognizing carbohydrates to generate a consistent immune response. They further investigated the mechanisms responsible for how carbohydrate-containing glycoconjugate vaccines activate protective immunity to a bacterial infection.
"One thing that is tremendously novel here is that we were able to find T-cells within a mouse after immunization with a glycoconjugate [vaccine] that just recognized carbohydrates," said Dennis L. Kasper, MD, director of BWH's Channing Laboratory. "So these may be the first true carbohydrate-specific T-cells found."
The understanding that it was not only proteins, but also carbohydrates that were being recognized by cells led researchers to design a vaccine that yielded many carbohydrate particles when processed by the immune systemin turn creating a vaccine that generated a stronger immune response. Researchers believe that the more effective vaccine prototype they designed may one day assist in protecting high-risk populations susceptible of disease.
"For example, pneumococcal conjugate vaccines are good in children, but are not effective in protecting the elderly," explained Kasper. So we are hopeful that by designing vaccines like this, you'll make better vaccines that will be effective in all the at-risk populations."
Fikri Avci, PhD, lead study author and instructor in the Department of Medicine at BWH and Harvard Medical School adds that the findings on how the body's immune cells interact with carbohydrates will also lead to more effective vaccines in the future.
"Carbohydrates are among the most abundant and structurally diverse molecules in nature," said Avci. "They are extremely important in many biological functions. A better understanding of carbohydrate interaction is crucial. We are hoping that our findings will provide a framework for production of new-generation therapeutics and preventive medicines not only against bacterial infections, but also for cancer and viral diseases."
###
The research was supported by grants from the United States National Institutes of Health.
Brigham and Women's Hospital (BWH) is a 793-bed nonprofit teaching affiliate of Harvard Medical School and a founding member of Partners HealthCare, an integrated health care delivery network. BWH is the home of the Carl J. and Ruth Shapiro Cardiovascular Center, the most advanced center of its kind. BWH is committed to excellence in patient care with expertise in virtually every specialty of medicine and surgery. The BWH medical preeminence dates back to 1832, and today that rich history in clinical care is coupled with its national leadership in quality improvement and patient safety initiatives and its dedication to educating and training the next generation of health care professionals. Through investigation and discovery conducted at its Biomedical Research Institute (BRI), www.brighamandwomens.org/research, BWH is an international leader in basic, clinical and translational research on human diseases, involving more than 900 physician-investigators and renowned biomedical scientists and faculty supported by more than $537 M in funding. BWH is also home to major landmark epidemiologic population studies, including the Nurses' and Physicians' Health Studies and the Women's Health Initiative. For more information about BWH, please visit www.brighamandwomens.org.
[ | E-mail | Share ] ?
AAAS and EurekAlert! are not responsible for the accuracy of news releases posted to EurekAlert! by contributing institutions or for the use of any information through the EurekAlert! system.
Source: http://www.eurekalert.org/pub_releases/2011-11/bawh-brd112811.php
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Report: Mystery blast near Iran nuke facility
TEHRAN?? Iran denied reports of a blast heard near a key nuclear facility on Tuesday, as new satellite pictures emerged of damage from an earlier explosion that left 17 dead at another location.
"In the afternoon, there was a noise like an explosion," provincial judiciary head Gholamreza Ansari was quoted as saying by ISNA news agency on Monday.
Mohammad-Mahdi Ismaili, Isfahan's deputy governor in political and security affairs, called the reports "sheer lies" on Tuesday, according the Jerusalem Post quoting the IRNA news agency.
An official from the city's fire department also denied that there had been an explosion, the newspaper said.
An important Iranian nuclear facility involved in processing uranium is located near Isfahan city, although Iranian media reports of the incident did not refer to it.
Story: Iranian protesters break into British Embassy in TehranA report on the explosion was published on the website of the Iranian news agency Fars on Monday, including a picture showing a thick column of black smoke, but it was removed after the incident was reported in Israel, according to Israeli website Haaretz.
Haaretz reported that Ismaili initially confirmed the blast and said the authorities were investigating the matter before later issuing denials.
Analysts speculated that this or other recent blasts could be the result of sabotage by other countries.
?While it?s impossible to confirm, recent events in Iran raise suspicions,? Gala Riani, a Middle East analyst at London-based forecaster IHS Global Insight told Bloomberg.
She told Bloomberg it was possible that ?foreign powers would want to carry out clandestine activity to sabotage Iran?s nuclear and military progress."
International Atomic Energy Agency spokeswoman Gill Tudor said the U.N. watchdog was aware of the media reports but had no further information.
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On November 12, a massive explosion at the Bid Kaneh military base 28 miles west of Tehran killed 17 Revolutionary Guards, including the head of the elite force's missile program.
Iran said that explosion, which could be heard as far away as the capital, was caused by an accident while weapons were being moved.
The Washington D.C.-based think tank, the Institute for Science and International Security, on Monday published an analysis of commercial satellite imagery of the base.
It said images taken before and after the blast showed most of the buildings on the compound appeared to be extensively damaged while some appeared to have been completely destroyed.
?Some of the destruction seen in the image may have also resulted from subsequent controlled demolition of buildings and removal of debris,? it said.
It said the blast occurred as Iran ?achieved a major milestone in the development of a new missile.?
?Iran was apparently performing a volatile procedure involving a missile engine at the site when the blast occurred,? it said.
Reuters contributed to this report
Source: http://www.msnbc.msn.com/id/45477062/ns/world_news-mideast_n_africa/
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Suicide bomber hits Iraq military base, 19 dead (Reuters)
BAGHDAD (Reuters) ? A suicide bomber attacked a military base in the Iraqi town of Taji on Monday, killing at least 19 people, in the latest assault by insurgents trying to undermine the government.
In central Baghdad an explosion in a car park at Iraq's parliament killed at least one person and wounded several others, including a politician, security officials said.
The Taji bombing was the third major attack in the last five days and underscored the fragile state of security as Washington prepares to pull out its remaining 14,500 troops by the end of the year, nearly nine years after the invasion that ousted Saddam Hussein.
The attacker detonated explosives packed into a minibus at the entrance to the base, which houses a jail holding prisoners from al Qaeda, the Mehdi Army militia and other groups, officials and security sources said. Taji is 20 km (12 miles) north of Baghdad.
"Today was the day for the prisoners to meet their families ... At the entrance, there was a minibus driven by a suicide bomber," said a duty officer at the jail. "It entered from the first checkpoint and before the police finished their search this guy drove quickly inside the base and blew it up."
Baghdad's security operations center said the blast killed 19 people, including 11 jail guards, and wounded 24 others.
Two other people were missing, security sources said.
Violence has dropped sharply since the peak of sectarian slaughter in 2006-07. But Iraqi security forces still struggle to contain daily attacks by Sunni Muslim insurgents tied to al Qaeda and rival Shi'ite Muslim militias.
Militants launch scores of bombings and other attacks every month. According to official government figures, 161 civilians were killed in violence in October, the highest toll of the year, along with 97 police and soldiers.
Iraqi and U.S. military officials have said Iraq may see an increase in attacks as American troops depart. Soldiers and police are frequent targets.
The explosion in the parking lot of the Iraqi parliament was caused by a mortar round, said Baghdad security spokesman Qassim al-Moussawi and several other sources. However, at least two sources at parliament said it was a car bomb.
Militants frequently lob mortars and rockets at Baghdad's heavily fortified Green Zone, which houses parliament, ministries and foreign embassies.
Two security sources said the blast killed one person and wounded six others. Two other police sources said three people died and nine were wounded.
Among those hurt was lawmaker Muayad al-Tayyeb, the spokesman for the Kurdish bloc in parliament, one of his colleagues said.
On Saturday attackers struck two areas around the Iraqi capital, killing at least 13 people and wounding more than 20 others. In the southern oil hub of Basra on Thursday three bombs exploded in a busy market, killing 21 and wounding 80.
The town of Taji, the site of a major Iraqi military base, was hit by bombers in July, when two blasts in the parking lot of a municipal government building killed at least 28 people and wounded scores of others.
On November 14, seven rockets landed in or near the U.S. military's Kalsu base near Iskandariya, 40 km (25 miles) south of Baghdad, wounding two Iraqi civilians living near the base, local police said.
(Writing by Jim Loney; Editing by David Stamp)
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Is Frontier Communications' 14% Dividend Yield Safe? | InvestorPlace
? ?
I?ve always been a big fan of Frontier Communications (NYSE:FTR). It?s a quiet little independent telecom company that handles regional services in just a few states like Northern California, Nevada, Arizona, Utah, Minnesota and New York. It?s the classic under-the-radar play that has done very well for investors over several years ? the kind of play you have to find in a specialized screen and one that also must execute its business well.
Things have gotten tough for the company, though. In its?recent third-quarter?report, the company told of a 30% decline in net income, and an 8% decline in revenue, led by a 12% drop in local and long-distance service revenues. Talk about a hang up! So what?s going on with Frontier and, more importantly, will its 13.7% yield remain intact?
The problem is that, like most other phone companies, Frontier is losing subscribers to cell phone service as folks cut their landlines. Residential customer count fell by 2.3% over the sequential quarter and 10% over the previous year. Business customers fell by almost the same rates. When you lose subscribers like that, you can expect to see revenue and net income get slammed as they did.
What?s hidden in these numbers is that the company bought almost 5 million landline customers from Verizon (NYSE:VZ) several quarters back and, as you might expect, that temporarily boosted revenue and earnings. Now, however, it?s comparison time and the chickens have come home to roost on those telephone wires, so to speak. The company has started new initiatives such as expanding Internet service and satellite TV services by partnering with the big players in that arena.
Still, the problem facing Frontier is that landlines are?going the way of the dodo bird. They won?t disappear entirely, but the company may continue losing customers until this trend abates. We?ve already seen Frontier cut its dividend ? it did so last year when it chopped it from a buck per share to 75 cents. The company?had to do it because?it had some big capital expenditures coming down the pike after buying those Verizon lines. Is there another cut in the company?s future?
I like to look at free cash flow to determine if a company is using too much of its assets to pay shareholders. So far this fiscal year, the company has had FCF of $1.21 billion and has paid out dividends of $560 million. That?s about a 2-1 ratio, so about 50% of free cash flow is going to dividends. That?s a perfectly acceptable ratio.
If Frontier continues to lose customers in large numbers, this dividend could be cut. However, if that happens, I don?t suspect it would be more than 50%, which means it would still pay a healthy dividend of almost 7%. Investors looking for rock-solid safety may want to avoid buying?now since the future is uncertain. Holders of the stock or those watching the company and trying to decide may want to think about holding for the next?two or?three quarters to see what develops.
Lawrence Meyers holds no positions in any stocks mentioned.
Source: http://www.investorplace.com/2011/11/is-frontier-communications-14-dividend-yield-safe/
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Govt fails to break impasse on retail reform (Reuters)
NEW DELHI (Reuters) ? Prime Minister Manmohan Singh failed to break an impasse on Tuesday, with opposition parties and his own political allies demanding a rollback of a reform allowing foreign supermarket giants to enter the country's $450 billion market.
The deadlock means Singh's Congress party-led coalition faces further opposition disruption of parliament -- which has been adjourned for six days already -- threatening other major bills, such as one on food subsidies for the poor.
The reform, which would allow global chains like Wal-Mart Stores Inc and Carrefour to own up to 51 percent of retail ventures, remains in limbo as talks between the government and political parties failed to make any breakthrough.
With a slender parliamentary majority, the government is dependent on its allies, but does not face any immediate threat of losing power.
Singh has several options.
He could reverse his cabinet's decision -- an unlikely move given it would be a major political set-back and damage India's image with sorely needed foreign investors just as Asia's third-largest economy is showing signs of slowing.
A more likely move would be to postpone the reform. The Hindu newspaper, quoting unnamed government sources, said the prime minister could refer the reform to a group of ministers, a traditional way of Congress kicking problems into the grass.
Or the government could just ignore the opposition and move ahead, risking political uproar.
"We are willing to discuss whatever the opposition wants, but they should allow the House to function," said Rajiv Shukla, junior parliamentary affairs minister.
Sonia Gandhi, the Congress party head who runs the government from behind the scenes, appeared to have been behind a move to water down the new rules and insist that foreign retailers source more goods from small Indian businesses.
That swift reversal showed how Singh's cabinet, many of them in their seventies, could be out of synch with Congress -- the latest sign of how Gandhi and her small team of loyal advisers can put politics first to water down reforms.
But the policy tweak did little to placate opponents.
"The government has implemented the policy of FDI in retail after lobbying of companies in the U.S. and other countries. We are totally against this," Murli Manohar Joshi, a leader of the Bharatiya Janata Party, said after the meeting.
A government ally, the Trinamool Congress party, which gives Congress a parliamentary majority, also wants a policy reversal.
INVESTORS WARY
The controversy comes at a bad time for Congress, worried the issue could become a lightning rod for criticism of the government before state elections due next year.
The issue feeds into some deep-seated nationalism of Indian politicians, as well as fears of massive job losses among the millions of small shopkeepers.
Indian shares were subdued on Tuesday as economic concerns came to the fore, and mounting political opposition to reforms unnerved investors.
Kaushik Basu, one of Singh's close advisers, said allowing global chains to open their first stores in India would be one of the most effective ways to help the country deal with food inflation, which stands close to 10 percent.
The economy, which grew at 8.5 percent in 2010/11, is widely expected to grow at around 7 percent this year, slowed by policy paralysis and a gloomy global outlook.
(Editing by Ian Geoghegan)
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Monday, November 28, 2011
Some questions, answers about the NBA labor deal
MIAMI (AP) ? No, the NBA lockout is not over. Not yet, but soon ? once owners and players approve the deal that would have NBA games resume on Christmas Day. Here's a look at some of the most prevalent questions about the state of things in the league right now.
___
Q: What happened to get this deal done?
A: As one person involved in the talks told The Associated Press, "sanity prevailed." Neither side was winning. Owners were losing money. Players were losing money. Fans were getting angry. Because Christmas is traditionally the day when the public really start watching NBA games, there was a late push to try and salvage the Dec. 25 schedule.
___
Q: So it's done?
A: Well, no. There's still a slew of issues to work through, and then there's the not-so-small matter of having owners and players actually vote on the deal. Though the deal's expected to be approved, it won't be unanimous as there are factions of hard-liners in both camps who will be unhappy with substantive portions of the deal.
___
Q: How could union chief Billy Hunter and president Derek Fisher "negotiate" with the NBA if the players' union had been disbanded?
A: When players dissolved the union that meant Hunter and Fisher no longer had the power to negotiate and agree to terms for the players. What could happen and what did happen with the NBA, as it did with the NFL this summer, is that lawyers and representatives for both sides can hold discussions under the guise of antitrust settlement talks. Hunter is an attorney. He knew the rules and the risks. Certainly, this could have blown up for the players and risked their antitrust lawsuit in Minnesota.
___
Q: What happens to that lawsuit?
A: Barring something crazy, the players will ask that it be dismissed. The league also must dismiss its New York lawsuit about the legality of the lockout.
___
Q: When will training camp start?
A: Dec. 9. Free agency is expected to begin then, too, meaning some locker rooms may as well start getting revolving doors installed now.
___
Q: And the first games?
A: The league wants three games on Christmas Day, and it's a safe bet the previously scheduled matchups ? Boston at New York, Miami at Dallas in a finals rematch, and Chicago at the Los Angeles Lakers ? will go on as planned. The Dec. 26 schedule and beyond? Get out your erasers. A lot will be changing.
___
Q: I don't understand. If there's deal, why is nothing happening for two weeks?
A: Clearly, you're not an attorney. Only the framework of a deal is in place. Now the rules, the language, the nuances, they all must be put to paper by the lawyers who will be charged with actually writing the new collective bargaining agreement. Until that's done, no players can be signed, traded, etc., since there are still no real operating rules by which teams would have to abide.
___
Q: How will the schedule work?
A: Still unclear. The easiest way to fill a 66-game schedule would have teams play four games against each divisional opponent (16 games) and two games against every other team in the league (50 games). It would also ensure that every team makes at least one appearance in every league arena, which is what fans would want anyway. A season without Kobe Bryant going to Madison Square Garden? Not happening.
___
Q: Will there be preseason games?
A: A person involved with the process tells The AP there will be, but details are still getting hammered out. (A good guess would have teams playing two games, probably against a nearby rival.) It's a strong possibility that those games will have reams of low-priced tickets, a gesture of apologizing to fans for the delay in getting basketball going again.
___
Q: What about the players who signed overseas? Can they come home?
A: In most cases, yes. New Jersey guard Deron Williams said on Twitter early Saturday that he would soon be leaving his Turkish club Besiktas. That team will not be thrilled to see him leave ? Williams had a 50-point game a few days ago. Some players who signed deals with Chinese clubs may have to work a bit harder (or, well, pay) to escape those contracts.
___
Q: What happens to these scheduled charity games, such as the "Homecoming Tour" featuring LeBron James, Dwyane Wade, Chris Paul and Carmelo Anthony, or Mario Chalmers' game in Alaska on Dec. 1?
A: Organizers were working Saturday to salvage at least some of them. Wade said he wanted to use the planned four-game tour he's involved with as a way to play competitive basketball before the season, even though he didn't know at the time when the season will begin. Although most players are in great shape, there's a big difference between that and "game shape." Frankly, a two-week training camp might not be enough time to get them there, either.
___
Follow Tim Reynolds on Twitter at http://www.twitter.com/ByTimReynolds
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Sunday, November 27, 2011
Alleged LA-area pepper-spraying shopper surrenders (AP)
A woman who allegedly fired pepper spray at other customers during a Black Friday sale has surrendered to authorities, Los Angeles police said Saturday.
Police Sgt. Jose Valle said the woman who allegedly caused minor injuries to 20 shoppers at a Los Angeles-area Walmart turned herself in Friday night.
She is currently not in custody but could face battery charges, Valle said. The woman's identity was not released, but police said they plan to release more details Saturday morning.
The attack took place about 10:20 p.m. Thursday shortly after doors opened for the sale. The store had brought out a crate of discounted Xbox video game players, and a crowd had formed to wait for the unwrapping. Valle says the woman began spraying people in order to get an advantage.
The incident was among those nationwide in which violence marred the traditional kickoff to the holiday shopping season.
In the most serious case, a robber shot a shopper who refused to give up his purchases outside a San Leandro, Calif., Walmart store, leaving the victim hospitalized in critical but stable condition.
Police in San Leandro, about 15 miles east of San Francisco, said the victim and his family were walking to their car around 1:45 a.m. Friday when they were confronted by a group of men who demanded their shopping items. When the family refused, a fight broke out, and one of the robbers pulled a gun and shot the man, said Sgt. Mike Sobek.
Meanwhile, police in suburban Phoenix came under fire when a video was posted online showing a 54-year-old grandfather on the floor of a Walmart store with a bloody face, after police said he was subdued Thursday night trying to shoplift during a chaotic rush for discounted video games.
The video, posted on YouTube, shows Jerald Allen Newman unconscious and bloodied as outraged customers yell expletives and say "that's police brutality" and "he wasn't doing anything."
In a police report that redacted the names of officers and witnesses, Newman's wife and other witnesses said he was just trying to help his grandson after the boy was trampled by shoppers, and only put a video game in his waistband to free his hands to help the boy.
Larry Hall, assistant chief of Buckeye police, said Newman was resisting arrest and it appeared the officer acted within reason.
Hall said the officer decided to do a leg sweep and take him to the ground but the man unfortunately hit his head.
"The store was incredibly crowded, and I was concerned about other customers' safety," the officer wrote in his police report.
Hall said Newman, who had a bloody nose and received four stitches on his forehead, was booked on suspicion of shoplifting and resisting arrest.
In Sacramento, Calif., a man was stabbed outside a mall Friday in an apparent gang-related incident as shoppers were hitting the stores.
The victim was taken to a hospital with non-life-threatening injuries, police said.
The stabbing stemmed from a fight between two groups around 3 a.m. in front of a Macy's department store at the Arden Fair Mall.
No arrests have been made. Police were hoping surveillance video will help identify the suspects.
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